Plissonnier, Marie-Laure <br/><br/>
The antidiabetic drug ciglitazone induces high grade bladder cancer cells apoptosis through the up-regulation of TRAIL.  [electronic resource] 

 -  PloS one  2011 
 - e28354 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0028354  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Apoptosis--drug effects<br/>BH3 Interacting Domain Death Agonist Protein--metabolism<br/>CASP8 and FADD-Like Apoptosis Regulating Protein--metabolism<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Cell Membrane--drug effects<br/>Enzyme Activation--drug effects<br/>G2 Phase--drug effects<br/>Humans<br/>Hypoglycemic Agents--pharmacology<br/>Inhibitor of Apoptosis Proteins--metabolism<br/>Mice<br/>Mitosis--drug effects<br/>Neoplasm Grading<br/>PPAR gamma--metabolism<br/>Proteasome Endopeptidase Complex--metabolism<br/>Receptors, Death Domain--metabolism<br/>Signal Transduction--drug effects<br/>Survivin<br/>TNF-Related Apoptosis-Inducing Ligand--metabolism<br/>Thiazolidinediones--pharmacology<br/>Transcriptional Activation--drug effects<br/>Up-Regulation--drug effects<br/>Urinary Bladder Neoplasms--drug therapy<br/>Xenograft Model Antitumor Assays