TY - GEN AU - Misra,Uma K AU - Pizzo,Salvatore V TI - Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex SN - 1097-4644 PY - 2012///0917 KW - Adaptor Proteins, Signal Transducing KW - metabolism KW - Carrier Proteins KW - Cell Line, Tumor KW - Chromones KW - pharmacology KW - Cyclic AMP KW - analogs & derivatives KW - Cyclic AMP Response Element-Binding Protein KW - Cyclic Nucleotide Phosphodiesterases, Type 3 KW - Cyclic Nucleotide Phosphodiesterases, Type 4 KW - Endoplasmic Reticulum Chaperone BiP KW - Gene Silencing KW - Guanine Nucleotide Exchange Factors KW - agonists KW - Humans KW - Male KW - Mechanistic Target of Rapamycin Complex 1 KW - Models, Biological KW - Morpholines KW - Multiprotein Complexes KW - Phosphorylation KW - Prostatic Neoplasms KW - genetics KW - Protein Multimerization KW - drug effects KW - Proteins KW - Proto-Oncogene Proteins c-akt KW - RNA-Binding Proteins KW - Rapamycin-Insensitive Companion of mTOR Protein KW - Regulatory-Associated Protein of mTOR KW - Ribosomal Protein S6 Kinases KW - Signal Transduction KW - Sirolimus KW - TOR Serine-Threonine Kinases KW - Thionucleotides KW - Up-Regulation N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/jcb.24018 ER -