Blackburn, Edith

A monoclonal antibody to the human HER3 receptor inhibits Neuregulin 1-beta binding and co-operates with Herceptin in inhibiting the growth of breast cancer derived cell lines. [electronic resource] - Breast cancer research and treatment Jul 2012 - 53-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1573-7217

10.1007/s10549-011-1908-1 doi


Antibodies, Monoclonal--pharmacology
Antibodies, Monoclonal, Humanized--pharmacology
Antineoplastic Agents--pharmacology
Binding, Competitive
Breast Neoplasms--drug therapy
Cell Line, Tumor--drug effects
Cell Proliferation--drug effects
Drug Screening Assays, Antitumor
Drug Synergism
Female
Humans
Neuregulin-1--metabolism
Protein Binding
Receptor, ErbB-3--antagonists & inhibitors
Trastuzumab