TY - GEN AU - Weiss,Glen J AU - Hidalgo,Manuel AU - Borad,Mitesh J AU - Laheru,Daniel AU - Tibes,Raoul AU - Ramanathan,Ramesh K AU - Blaydorn,Lisa AU - Jameson,Gayle AU - Jimeno,Antonio AU - Isaacs,Jeffrey D AU - Scaburri,Angela AU - Pacciarini,Maria Adele AU - Fiorentini,Francesco AU - Ciomei,Marina AU - Von Hoff,Daniel D TI - Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies SN - 1573-0646 PY - 2013///0404 KW - Adolescent KW - Adult KW - Aged KW - Cyclin-Dependent Kinases KW - antagonists & inhibitors KW - Drug Administration Schedule KW - Female KW - Humans KW - Male KW - Maximum Tolerated Dose KW - Middle Aged KW - Neoplasms KW - drug therapy KW - Protein Kinase Inhibitors KW - administration & dosage KW - Pyrazoles KW - Quinazolines KW - Receptor, trkA KW - Treatment Outcome KW - Young Adult N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study UR - https://doi.org/10.1007/s10637-011-9774-6 ER -