TY - GEN AU - Yun,Hee Jung AU - Hyun,Sook Kyung AU - Park,Jung Ha AU - Kim,Byung Woo AU - Kwon,Hyun Ju TI - Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells SN - 1573-4919 PY - 2012///0702 KW - Adenocarcinoma KW - enzymology KW - Animals KW - Antineoplastic Agents, Phytogenic KW - pharmacology KW - Apoptosis KW - drug effects KW - Benzocycloheptenes KW - Cell Cycle Proteins KW - metabolism KW - Checkpoint Kinase 2 KW - Colonic Neoplasms KW - Cyclin-Dependent Kinase Inhibitor p21 KW - DNA Breaks, Double-Stranded KW - DNA-Binding Proteins KW - Fibroblasts KW - G1 Phase Cell Cycle Checkpoints KW - HT29 Cells KW - Histones KW - Humans KW - Mice KW - Minichromosome Maintenance Complex Component 4 KW - Nuclear Proteins KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - Signal Transduction KW - Time Factors KW - Tumor Suppressor Protein p53 KW - cdc25 Phosphatases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s11010-011-1180-z ER -