Patro, Birija Sankar

WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes. [electronic resource] - Journal of cell science Dec 2011 - 3967-79 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

1477-9137

10.1242/jcs.081372 doi


Ataxia Telangiectasia Mutated Proteins
Camptothecin--pharmacology
Cell Cycle Proteins--genetics
Cell Line, Tumor
Checkpoint Kinase 1
Chromatin--genetics
Chromatin Immunoprecipitation
DNA Damage
DNA Replication
DNA, Single-Stranded--genetics
Exodeoxyribonucleases--genetics
Gene Expression Regulation, Enzymologic
Gene Knockdown Techniques
Genomic Instability
Humans
Hydroxyurea--pharmacology
Phosphorylation
Protein Kinases--genetics
Protein Serine-Threonine Kinases--genetics
RNA, Small Interfering--genetics
RecQ Helicases--genetics
S Phase Cell Cycle Checkpoints
Topoisomerase I Inhibitors--pharmacology
Werner Syndrome Helicase