TY  - GEN
AU  - Lee,Wing-Kee
AU  - Braun,Matthias
AU  - Langelüddecke,Christian
AU  - Thévenod,Frank
TI  - Cyclosporin a, but not FK506, induces osmotic lysis of pancreas zymogen granules, intra-acinar enzyme release, and lysosome instability by activating K+ channel
SN  - 1536-4828
PY  - 2012///0816
KW  - Acinar Cells
KW  - drug effects
KW  - Amylases
KW  - metabolism
KW  - Animals
KW  - Biomarkers
KW  - Cathepsin B
KW  - Cyclosporine
KW  - adverse effects
KW  - Immunosuppressive Agents
KW  - Lysosomes
KW  - Male
KW  - Osmosis
KW  - Pancreas
KW  - blood supply
KW  - Pancreas Transplantation
KW  - Pancreatitis, Graft
KW  - etiology
KW  - Permeability
KW  - Potassium Channels
KW  - Rats
KW  - Rats, Wistar
KW  - Reperfusion Injury
KW  - Secretory Vesicles
KW  - Tacrolimus
KW  - pharmacology
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1097/MPA.0b013e318239c6e5
ER  -