Lee, Wing-Kee <br/><br/>
Cyclosporin a, but not FK506, induces osmotic lysis of pancreas zymogen granules, intra-acinar enzyme release, and lysosome instability by activating K+ channel.  [electronic resource] 

 -  Pancreas  May 2012 
 - 596-604 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1536-4828 
<br/><br/><label>Standard No.: </label>10.1097/MPA.0b013e318239c6e5  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acinar Cells--drug effects<br/>Amylases--metabolism<br/>Animals<br/>Biomarkers--metabolism<br/>Cathepsin B--metabolism<br/>Cyclosporine--adverse effects<br/>Immunosuppressive Agents--adverse effects<br/>Lysosomes--drug effects<br/>Male<br/>Osmosis--drug effects<br/>Pancreas--blood supply<br/>Pancreas Transplantation<br/>Pancreatitis, Graft--etiology<br/>Permeability--drug effects<br/>Potassium Channels--drug effects<br/>Rats<br/>Rats, Wistar<br/>Reperfusion Injury--etiology<br/>Secretory Vesicles--drug effects<br/>Tacrolimus--pharmacology