TY  - GEN
AU  - Stokes,Suzanne S
AU  - Gowravaram,Madhusudhan
AU  - Huynh,Hoan
AU  - Lu,Min
AU  - Mullen,George B
AU  - Chen,Brendan
AU  - Albert,Robert
AU  - O'Shea,Thomas J
AU  - Rooney,Michael T
AU  - Hu,Haiqing
AU  - Newman,Joseph V
AU  - Mills,Scott D
TI  - Discovery of bacterial NAD⁺-dependent DNA ligase inhibitors: improvements in clearance of adenosine series
SN  - 1464-3405
PY  - 2012///0803
KW  - Adenine
KW  - chemistry
KW  - Adenosine
KW  - Administration, Oral
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - chemical synthesis
KW  - Biological Availability
KW  - Chromatography, Liquid
KW  - methods
KW  - DNA Ligases
KW  - antagonists & inhibitors
KW  - Dogs
KW  - Drug Design
KW  - Drug Evaluation, Preclinical
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Fluorine
KW  - Inhibitory Concentration 50
KW  - Mass Spectrometry
KW  - Models, Chemical
KW  - NAD
KW  - Rats
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2011.11.071
ER  -