TY - GEN AU - Liu,Bing AU - Geng,Guoyan AU - Lin,Rongtuan AU - Ren,Cuiyan AU - Wu,Jian Hui TI - Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants SN - 1747-0285 PY - 2012///0514 KW - Androgen Receptor Antagonists KW - chemistry KW - Anilides KW - Binding Sites KW - Cell Line, Tumor KW - Enzyme Activation KW - drug effects KW - Humans KW - I-kappa B Kinase KW - metabolism KW - Interleukin-6 KW - Molecular Dynamics Simulation KW - Mutation KW - Nitriles KW - Nucleosides KW - Protein Structure, Tertiary KW - Receptors, Androgen KW - Tosyl Compounds KW - Triazines N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1747-0285.2011.01290.x ER -