TY - GEN AU - Koole,Cassandra AU - Wootten,Denise AU - Simms,John AU - Miller,Laurence J AU - Christopoulos,Arthur AU - Sexton,Patrick M TI - Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation SN - 1083-351X PY - 2012///0325 KW - Amino Acid Substitution KW - Animals KW - CHO Cells KW - Cricetinae KW - Cricetulus KW - Cyclic AMP KW - chemistry KW - Glucagon-Like Peptide 1 KW - Glucagon-Like Peptide-1 Receptor KW - Humans KW - MAP Kinase Signaling System KW - drug effects KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Mutation, Missense KW - Peptides KW - Protein Binding KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Receptors, Glucagon KW - agonists N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M111.309328 ER -