TY - GEN AU - Zhou,Xiaobo AU - Baron,Rebecca M AU - Hardin,Megan AU - Cho,Michael H AU - Zielinski,Jan AU - Hawrylkiewicz,Iwona AU - Sliwinski,Pawel AU - Hersh,Craig P AU - Mancini,John D AU - Lu,Ke AU - Thibault,Derek AU - Donahue,Amy L AU - Klanderman,Barbara J AU - Rosner,Bernard AU - Raby,Benjamin A AU - Lu,Quan AU - Geldart,Adriana M AU - Layne,Matthew D AU - Perrella,Mark A AU - Weiss,Scott T AU - Choi,Augustine M K AU - Silverman,Edwin K TI - Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP SN - 1460-2083 PY - 2012///0807 KW - Adult KW - Aged KW - Aged, 80 and over KW - Alleles KW - Blotting, Western KW - Bronchi KW - cytology KW - Carrier Proteins KW - genetics KW - Case-Control Studies KW - Cells, Cultured KW - Chromatin Immunoprecipitation KW - Chromosome Mapping KW - Chromosomes, Human, Pair 4 KW - Electrophoretic Mobility Shift Assay KW - Enhancer Elements, Genetic KW - Female KW - Fibroblasts KW - Genetic Predisposition to Disease KW - Genotype KW - Haplotypes KW - Humans KW - Lung KW - Male KW - Membrane Glycoproteins KW - Middle Aged KW - Polymorphism, Single Nucleotide KW - Prognosis KW - Promoter Regions, Genetic KW - Pulmonary Disease, Chronic Obstructive KW - Real-Time Polymerase Chain Reaction KW - Smoking KW - Sp3 Transcription Factor KW - metabolism N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1093/hmg/ddr569 ER -