Li, Cheng <br/><br/>
Effects of baicalein on the pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats: possible role of cytochrome P450 3A4 and P-glycoprotein inhibition by baicalein.  [electronic resource] 

 -  Archives of pharmacal research  Nov 2011 
 - 1965-72 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1976-3786 
<br/><br/><label>Standard No.: </label>10.1007/s12272-011-1117-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--antagonists & inhibitors<br/>Animals<br/>Antineoplastic Agents, Hormonal--blood<br/>Biotransformation--drug effects<br/>Cell Line<br/>Cytochrome P-450 CYP3A--genetics<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Dose-Response Relationship, Drug<br/>Drug Interactions<br/>Enzyme Inhibitors--administration & dosage<br/>Flavanones--administration & dosage<br/>Half-Life<br/>Humans<br/>Male<br/>Membrane Transport Modulators--administration & dosage<br/>Metabolic Clearance Rate--drug effects<br/>Rats<br/>Rats, Sprague-Dawley<br/>Recombinant Proteins--antagonists & inhibitors<br/>Tamoxifen--analogs & derivatives