van Westen, Gerard J P <br/><br/>
Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development.  [electronic resource] 

 -  PloS one  2011 
 - e27518 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0027518  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Binding Sites<br/>Databases as Topic<br/>Drug Evaluation, Preclinical--methods<br/>HIV Reverse Transcriptase--antagonists & inhibitors<br/>Humans<br/>Ligands<br/>Models, Molecular<br/>Molecular Sequence Data<br/>Mutation--genetics<br/>Proteomics--methods<br/>Reproducibility of Results<br/>Reverse Transcriptase Inhibitors--analysis