Fryer, Ryan M <br/><br/>
Mitigation of off-target adrenergic binding and effects on cardiovascular function in the discovery of novel ribosomal S6 kinase 2 inhibitors.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Mar 2012 
 - 492-500 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-0103 
<br/><br/><label>Standard No.: </label>10.1124/jpet.111.189365  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Azepines--pharmacology<br/>Benzimidazoles--pharmacology<br/>Blood Pressure--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Discovery<br/>Male<br/>Protein Kinase Inhibitors--pharmacology<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptors, Adrenergic, alpha-1--metabolism<br/>Receptors, Adrenergic, alpha-2--metabolism<br/>Ribosomal Protein S6 Kinases, 90-kDa--antagonists & inhibitors