Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism. [electronic resource]
- Cell regulation Mar 1990
- 379-90 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
1044-2030
10.1091/mbc.1.4.379 doi
Animals Cell Division--drug effects Cell Line DNA Replication--drug effects DNA-Binding Proteins--biosynthesis Diglycerides--metabolism Endothelins--pharmacology Epidermal Growth Factor--pharmacology Fibroblasts--drug effects Gene Expression Regulation--drug effects Histones--metabolism Phosphorylation Protein Kinase C--antagonists & inhibitors Protein Processing, Post-Translational--drug effects Proto-Oncogene Proteins--biosynthesis Proto-Oncogene Proteins c-fos Proto-Oncogene Proteins c-jun Rats Second Messenger Systems--drug effects Stimulation, Chemical Tetradecanoylphorbol Acetate--pharmacology Transcription Factors--biosynthesis Transcription, Genetic--drug effects