TY  - GEN
AU  - Portoghese,P S
AU  - Larson,D L
AU  - Jiang,J B
AU  - Caruso,T P
AU  - Takemori,A E
TI  - Synthesis and pharmacologic characterization of an alkylating analogue (chlornaltrexamine) of naltrexone with ultralong-lasting narcotic antagonist properties
SN  - 0022-2623
PY  - 1979///0523
KW  - Alkylating Agents
KW  - chemical synthesis
KW  - Analgesics
KW  - Animals
KW  - Humans
KW  - In Vitro Techniques
KW  - Male
KW  - Mice
KW  - Molecular Conformation
KW  - Morphine
KW  - antagonists & inhibitors
KW  - Morphine Dependence
KW  - prevention & control
KW  - Naloxone
KW  - analogs & derivatives
KW  - Naltrexone
KW  - Narcotic Antagonists
KW  - Nitrogen Mustard Compounds
KW  - Rats
KW  - Receptors, Opioid
KW  - metabolism
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1021/jm00188a008
ER  -