TY  - GEN
AU  - Gong,Inna Y
AU  - Schwarz,Ute I
AU  - Crown,Natalie
AU  - Dresser,George K
AU  - Lazo-Langner,Alejandro
AU  - Zou,GuangYong
AU  - Roden,Dan M
AU  - Stein,C Michael
AU  - Rodger,Marc
AU  - Wells,Philip S
AU  - Kim,Richard B
AU  - Tirona,Rommel G
TI  - Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation
SN  - 1932-6203
PY  - 2012///0503
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Algorithms
KW  - Anticoagulants
KW  - pharmacokinetics
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Blood Coagulation
KW  - drug effects
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 Enzyme System
KW  - Cytochrome P450 Family 4
KW  - Dose-Response Relationship, Drug
KW  - Female
KW  - Gene Frequency
KW  - Genotype
KW  - Humans
KW  - Kidney Function Tests
KW  - Male
KW  - Middle Aged
KW  - Mixed Function Oxygenases
KW  - Prospective Studies
KW  - Tissue Distribution
KW  - Vitamin K
KW  - metabolism
KW  - Vitamin K Epoxide Reductases
KW  - Warfarin
KW  - Young Adult
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0027808
ER  -