TY - GEN AU - Sapetto-Rebow,Beata AU - McLoughlin,Sarah C AU - O'Shea,Lynne C AU - O'Leary,Olivia AU - Willer,Jason R AU - Alvarez,Yolanda AU - Collery,Ross AU - O'Sullivan,Jacintha AU - Van Eeden,Freek AU - Hensey,Carmel AU - Kennedy,Breandán N TI - Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants SN - 1471-213X PY - 2012///0608 KW - Animals KW - Antigens, Neoplasm KW - genetics KW - Base Sequence KW - Cell Cycle KW - Cell Extracts KW - DNA Topoisomerases, Type II KW - DNA-Binding Proteins KW - antagonists & inhibitors KW - Diketopiperazines KW - Embryonic Development KW - Female KW - Gene Expression KW - Gene Knockout Techniques KW - Genes, Recessive KW - Isoenzymes KW - Male KW - Phenotype KW - Phylogeny KW - Piperazines KW - pharmacology KW - Point Mutation KW - Poly-ADP-Ribose Binding Proteins KW - Sequence Analysis, DNA KW - Viviparity, Nonmammalian KW - Xenopus KW - Zebrafish KW - embryology KW - Zebrafish Proteins KW - Zygote KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/1471-213X-11-71 ER -