TY - GEN AU - Mürdter,Thomas E AU - Kerb,Reinhold AU - Turpeinen,Miia AU - Schroth,Werner AU - Ganchev,Boian AU - Böhmer,Gabriele M AU - Igel,Svitlana AU - Schaeffeler,Elke AU - Zanger,Ulrich AU - Brauch,Hiltrud AU - Schwab,Matthias TI - Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites SN - 1460-2083 PY - 2012///0705 KW - Biotransformation KW - Clomiphene KW - analogs & derivatives KW - Cytochrome P-450 CYP2D6 KW - genetics KW - Estrogen Antagonists KW - metabolism KW - Female KW - Genotype KW - Humans KW - Microsomes, Liver KW - Molecular Structure KW - Polymorphism, Genetic KW - Receptors, Estrogen KW - antagonists & inhibitors KW - Recombinant Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/hmg/ddr543 ER -