Wise, David R <br/><br/>
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Dec 2011 
 - 19611-6 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1117773108  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Carboxylic Acids--metabolism<br/>Cell Hypoxia<br/>Cell Line, Tumor<br/>Cell Proliferation<br/>Cell Survival<br/>Citrates--metabolism<br/>Citric Acid Cycle<br/>Gas Chromatography-Mass Spectrometry<br/>Glucose--metabolism<br/>Glutamine--metabolism<br/>Humans<br/>Hypoxia-Inducible Factor 1--genetics<br/>Immunoblotting<br/>Isocitrate Dehydrogenase--genetics<br/>Ketoglutaric Acids--metabolism<br/>Neoplasms--genetics<br/>Oxidation-Reduction<br/>RNA Interference