TY - GEN AU - Fuka,G AU - Kantner,H-P AU - Grausenburger,R AU - Inthal,A AU - Bauer,E AU - Krapf,G AU - Kaindl,U AU - Kauer,M AU - Dworzak,M N AU - Stoiber,D AU - Haas,O A AU - Panzer-Grümayer,R TI - Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts SN - 1476-5551 PY - 2012///0705 KW - Animals KW - Cell Line, Tumor KW - Core Binding Factor Alpha 2 Subunit KW - genetics KW - Gene Silencing KW - Humans KW - Mice KW - Phosphatidylinositol 3-Kinases KW - metabolism KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-ets KW - RNA Interference KW - Real-Time Polymerase Chain Reaction KW - Repressor Proteins KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - Transplantation, Heterologous KW - ETS Translocation Variant 6 Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/leu.2011.322 ER -