TY  - GEN
AU  - Morley,Andrew D
AU  - King,Sarah
AU  - Roberts,Bryan
AU  - Lever,Sarah
AU  - Teobald,Barry
AU  - Fisher,Adrian
AU  - Cook,Tony
AU  - Parker,Beth
AU  - Wenlock,Mark
AU  - Phillips,Caroline
AU  - Grime,Ken
TI  - Lead optimisation of pyrazoles as novel FPR1 antagonists
SN  - 1464-3405
PY  - 2012///0803
KW  - Animals
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - Chemistry, Physical
KW  - Drug Design
KW  - Hepatocytes
KW  - cytology
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Male
KW  - Microsomes, Liver
KW  - metabolism
KW  - Models, Chemical
KW  - Pyrazoles
KW  - chemical synthesis
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Receptors, Formyl Peptide
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2011.10.090
ER  -