TY - GEN AU - Niewold,Timothy B AU - Kelly,Jennifer A AU - Kariuki,Silvia N AU - Franek,Beverly S AU - Kumar,Akaash A AU - Kaufman,Kenneth M AU - Thomas,Kenaz AU - Walker,Daniel AU - Kamp,Stan AU - Frost,Jacqueline M AU - Wong,Andrew K AU - Merrill,Joan T AU - Alarcón-Riquelme,Marta E AU - Tikly,Mohammed AU - Ramsey-Goldman,Rosalind AU - Reveille,John D AU - Petri,Michelle A AU - Edberg,Jeffrey C AU - Kimberly,Robert P AU - Alarcón,Graciela S AU - Kamen,Diane L AU - Gilkeson,Gary S AU - Vyse,Timothy J AU - James,Judith A AU - Gaffney,Patrick M AU - Moser,Kathy L AU - Crow,Mary K AU - Harley,John B TI - IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus SN - 1468-2060 PY - 2012///0402 KW - Black or African American KW - genetics KW - Antibodies, Antinuclear KW - blood KW - Autoantibodies KW - Case-Control Studies KW - DNA KW - immunology KW - Genetic Predisposition to Disease KW - Genotype KW - Haplotypes KW - Humans KW - Interferon Regulatory Factors KW - Interferon-alpha KW - Lupus Erythematosus, Systemic KW - Polymorphism, Single Nucleotide KW - White People N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1136/annrheumdis-2011-200463 ER -