TY - GEN AU - Ellis,Leigh AU - Lehet,Kristin AU - Ramakrishnan,Swathi AU - Adelaiye,Remi AU - Miles,Kiersten M AU - Wang,Dan AU - Liu,Song AU - Atadja,Peter AU - Carducci,Michael A AU - Pili,Roberto TI - Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression SN - 1932-6203 PY - 2012///0518 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Drug Synergism KW - Everolimus KW - Genes, myc KW - Histone Deacetylase Inhibitors KW - Hydroxamic Acids KW - Hypoxia KW - metabolism KW - Indoles KW - Male KW - Mice KW - Mice, Transgenic KW - MicroRNAs KW - genetics KW - Panobinostat KW - Prostatic Neoplasms KW - drug therapy KW - Receptors, Androgen KW - Signal Transduction KW - Sirolimus KW - analogs & derivatives KW - TOR Serine-Threonine Kinases KW - antagonists & inhibitors KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1371/journal.pone.0027178 ER -