Ikejima, M

The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA. [electronic resource] - The Journal of biological chemistry Dec 1990 - 21907-13 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0021-9258


Amino Acid Sequence
Base Sequence
Cloning, Molecular
Cysteine--physiology
DNA--metabolism
DNA Damage
DNA Mutational Analysis
DNA Repair
DNA-Binding Proteins--genetics
Enzyme Activation
Humans
Molecular Sequence Data
Poly(ADP-ribose) Polymerases--genetics
Structure-Activity Relationship
Substrate Specificity
Zinc Fingers