Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase. [electronic resource]
- The Journal of biological chemistry Dec 2011
- 43596-43600 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.C111.317628 doi
Animals Autoimmune Diseases--genetics Autoimmune Diseases of the Nervous System--genetics Catalysis Cattle Deoxyguanine Nucleotides--chemistry Dose-Response Relationship, Drug HIV-1--genetics Humans Mice Monomeric GTP-Binding Proteins--chemistry Myeloid Cells--cytology Nervous System Malformations--genetics Nucleosides--chemistry Phosphoric Monoester Hydrolases--chemistry SAM Domain and HD Domain-Containing Protein 1 Viral Regulatory and Accessory Proteins--metabolism Virus Replication