TY - GEN AU - Lu,Yongke AU - Leung,Tung Ming AU - Ward,Stephen C AU - Nieto,Natalia TI - Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress SN - 1522-1547 PY - 2012///0423 KW - Alanine Transaminase KW - blood KW - Animals KW - Apoptosis KW - drug effects KW - Arginine KW - metabolism KW - Argininosuccinate Synthase KW - deficiency KW - Aspartate Aminotransferases KW - Caspase 3 KW - Chemical and Drug Induced Liver Injury KW - Dual Specificity Phosphatase 1 KW - Gene Expression KW - JNK Mitogen-Activated Protein Kinases KW - Lipopolysaccharides KW - pharmacology KW - Liver KW - Mice KW - Mice, 129 Strain KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Neutrophils KW - pathology KW - Nitrates KW - Nitric Oxide Synthase Type II KW - Nitrites KW - Nitrosation KW - Phosphorylation KW - Proteins KW - Pyrazoles KW - Receptors, Tumor Necrosis Factor, Type I KW - genetics KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1152/ajpgi.00375.2011 ER -