Thomas, F <br/><br/>
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.  [electronic resource] 

 -  British journal of cancer  Nov 2011 
 - 1654-62 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1532-1827 
<br/><br/><label>Standard No.: </label>10.1038/bjc.2011.442  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Antimetabolites, Antineoplastic--administration & dosage<br/>Antineoplastic Combined Chemotherapy Protocols--adverse effects<br/>Camptothecin--administration & dosage<br/>Chemoradiotherapy, Adjuvant--adverse effects<br/>Disease-Free Survival<br/>Fluorouracil--administration & dosage<br/>Genotype<br/>Humans<br/>Irinotecan<br/>Methylenetetrahydrofolate Reductase (NADPH2)--genetics<br/>Middle Aged<br/>Pharmacogenetics--methods<br/>Polymorphism, Genetic<br/>Prospective Studies<br/>Radiation-Sensitizing Agents--administration & dosage<br/>Rectal Neoplasms--enzymology<br/>Treatment Outcome<br/>Young Adult