TY - GEN AU - Ran,Yong AU - Liu,Tian-Tian AU - Zhou,Qian AU - Li,Shu AU - Mao,Ai-Ping AU - Li,Ying AU - Liu,Li-Juan AU - Cheng,Jin-Ke AU - Shu,Hong-Bing TI - SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation SN - 1759-4685 PY - 2012///0315 KW - Animals KW - Cysteine Endopeptidases KW - genetics KW - Endopeptidases KW - HEK293 Cells KW - Humans KW - Immunity, Innate KW - immunology KW - Interferon Regulatory Factor-3 KW - Interferon-beta KW - metabolism KW - Mice KW - Mice, Knockout KW - Multienzyme Complexes KW - RNA Interference KW - Sendai virus KW - Signal Transduction KW - Small Ubiquitin-Related Modifier Proteins KW - Sumoylation KW - Ubiquitination KW - Virus Replication N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/jmcb/mjr020 ER -