Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth. [electronic resource]
- Cancer science Feb 2012
- 369-74 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1349-7006
10.1111/j.1349-7006.2011.02123.x doi
Animals Cell Line Cell Line, Tumor Cell Proliferation--drug effects Cell Transformation, Viral Gene Products, tax--genetics Human T-lymphotropic virus 1 Humans Interleukin-2--metabolism Mice Mutation Oncogene Protein v-akt--metabolism Phosphorylation Ribosomal Protein S6 Kinases, 70-kDa--metabolism Sirolimus--pharmacology T-Lymphocytes--physiology TOR Serine-Threonine Kinases--antagonists & inhibitors