TY - GEN AU - Poulin,Patrick AU - Kenny,Jane R AU - Hop,Cornelis E C A AU - Haddad,Sami TI - In vitro-in vivo extrapolation of clearance: modeling hepatic metabolic clearance of highly bound drugs and comparative assessment with existing calculation methods SN - 1520-6017 PY - 2012///0511 KW - Humans KW - In Vitro Techniques KW - Liver KW - metabolism KW - Models, Theoretical KW - Pharmacokinetics N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jps.22792 ER -