Wolf, Dennis

Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice. [electronic resource] - Circulation research Nov 2011 - 1269-79 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1524-4571

10.1161/CIRCRESAHA.111.247684 doi


Amino Acid Motifs
Animals
Atherosclerosis--genetics
Bleeding Time
Blood Coagulation--drug effects
CD40 Ligand--metabolism
CHO Cells
Cells, Cultured
Chemotaxis, Leukocyte--physiology
Cricetinae
Humans
Macrophage-1 Antigen--metabolism
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Molecular
Peptide Fragments--pharmacology
Peptides, Cyclic--pharmacology
Peritonitis--blood
Protein Conformation
Protein Interaction Mapping
Protein Structure, Tertiary
Receptors, LDL--deficiency
Recombinant Fusion Proteins--physiology
Surface Plasmon Resonance
Thrombosis--etiology