TY - GEN AU - Sarcar,Bhaswati AU - Kahali,Soumen AU - Prabhu,Antony H AU - Shumway,Stuart D AU - Xu,Yang AU - Demuth,Tim AU - Chinnaiyan,Prakash TI - Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines SN - 1538-8514 PY - 2012///0511 KW - Animals KW - Brain Neoplasms KW - drug therapy KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Cell Line, Tumor KW - G2 Phase Cell Cycle Checkpoints KW - drug effects KW - Glioblastoma KW - Humans KW - Mice KW - Mice, Nude KW - Molecular Targeted Therapy KW - Nuclear Proteins KW - Protein Kinase Inhibitors KW - pharmacokinetics KW - Protein-Tyrosine Kinases KW - Pyrazoles KW - Pyrimidines KW - Pyrimidinones KW - Radiation Tolerance KW - Radiation-Sensitizing Agents KW - Up-Regulation KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1535-7163.MCT-11-0469 ER -