TY  - GEN
AU  - Westerhausen,A
AU  - Kishi,J
AU  - Prockop,D J
TI  - Mutations that substitute serine for glycine alpha 1-598 and glycine alpha 1-631 in type I procollagen. The effects on thermal unfolding of the triple helix are position-specific and demonstrate that the protein unfolds through a series of cooperative blocks
SN  - 0021-9258
PY  - 1990///0913
KW  - Base Sequence
KW  - Cells, Cultured
KW  - Codon
KW  - genetics
KW  - DNA
KW  - Fibroblasts
KW  - metabolism
KW  - Glycine
KW  - Humans
KW  - Infant, Newborn
KW  - Infant, Premature
KW  - Male
KW  - Models, Structural
KW  - Molecular Sequence Data
KW  - Mutation
KW  - Oligonucleotide Probes
KW  - Osteogenesis Imperfecta
KW  - Polymerase Chain Reaction
KW  - Procollagen
KW  - Protein Conformation
KW  - Protein Denaturation
KW  - Serine
KW  - Skin
KW  - Templates, Genetic
N1  - Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -