Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. [electronic resource]
- Molecular pharmacology Jan 2012
- 63-72 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1521-0111
10.1124/mol.111.075192 doi
Alleles Animals Cell Line Cytochrome P-450 CYP2D6--metabolism Drug Interactions--physiology Embryonic Stem Cells--enzymology Genetic Variation Humans Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Models, Animal