Park, Ji Hye <br/><br/>
A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells.  [electronic resource] 

 -  Investigational new drugs  Oct 2012 
 - 1887-98 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1573-0646 
<br/><br/><label>Standard No.: </label>10.1007/s10637-011-9752-z  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents, Hormonal--pharmacology<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--genetics<br/>Autophagy--drug effects<br/>Beclin-1<br/>Breast Neoplasms--drug therapy<br/>Caspases--genetics<br/>Cell Cycle Checkpoints--drug effects<br/>Cell Death--drug effects<br/>Cell Division--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Drug Resistance, Neoplasm<br/>Female<br/>G2 Phase--drug effects<br/>Histone Deacetylase Inhibitors--pharmacology<br/>Histone Deacetylases--genetics<br/>Humans<br/>MCF-7 Cells<br/>Membrane Proteins--genetics<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Phenyl Ethers--pharmacology<br/>Pimelic Acids--pharmacology<br/>Proliferating Cell Nuclear Antigen--genetics<br/>Tamoxifen--pharmacology<br/>Xenograft Model Antitumor Assays