TY - GEN AU - Nebbioso,Angela AU - Pereira,Raquel AU - Khanwalkar,Harshal AU - Matarese,Filomena AU - García-Rodríguez,José AU - Miceli,Marco AU - Logie,Colin AU - Kedinger,Valerie AU - Ferrara,Felicetto AU - Stunnenberg,Hendrik G AU - de Lera,Angel R AU - Gronemeyer,Hinrich AU - Altucci,Lucia TI - Death receptor pathway activation and increase of ROS production by the triple epigenetic inhibitor UVI5008 SN - 1538-8514 PY - 2012///0511 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Cells, Cultured KW - Disulfides KW - Down-Regulation KW - drug effects KW - Epigenesis, Genetic KW - Female KW - HCT116 Cells KW - HL-60 Cells KW - Humans KW - K562 Cells KW - Mice KW - Mice, Nude KW - Oximes KW - Reactive Oxygen Species KW - metabolism KW - Receptors, Death Domain KW - agonists KW - Signal Transduction KW - U937 Cells KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1535-7163.MCT-11-0525 ER -