TY - GEN AU - Aburahma,Mona Hassan AU - Mahmoud,Azza Ahmed TI - Biodegradable ocular inserts for sustained delivery of brimonidine tartarate: preparation and in vitro/in vivo evaluation SN - 1530-9932 PY - 2012///0326 KW - Absorbable Implants KW - Acrylic Resins KW - Administration, Ophthalmic KW - Adrenergic alpha-2 Receptor Agonists KW - administration & dosage KW - Alginates KW - chemistry KW - Animals KW - Brimonidine Tartrate KW - Calorimetry, Differential Scanning KW - Cellulose KW - analogs & derivatives KW - Chemistry, Pharmaceutical KW - Chitosan KW - Delayed-Action Preparations KW - Disease Models, Animal KW - Drug Carriers KW - Drug Compounding KW - Glaucoma KW - drug therapy KW - Glucuronic Acid KW - Hexuronic Acids KW - Hydrophobic and Hydrophilic Interactions KW - Hypromellose Derivatives KW - Intraocular Pressure KW - drug effects KW - Kinetics KW - Methylcellulose KW - Ophthalmic Solutions KW - Polymers KW - Polymethacrylic Acids KW - Polyvinyls KW - Povidone KW - Quinoxalines KW - Rabbits KW - Solubility KW - Spectroscopy, Fourier Transform Infrared KW - Technology, Pharmaceutical KW - methods KW - X-Ray Diffraction N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1208/s12249-011-9701-3 ER -