Design and development of a peptide-based adiponectin receptor agonist for cancer treatment. [electronic resource]
- BMC biotechnology Oct 2011
- 90 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1472-6750
10.1186/1472-6750-11-90 doi
Adiponectin--chemistry Animals Breast Neoplasms--drug therapy Cell Line, Tumor Dose-Response Relationship, Drug Drug Design Female Humans Injections, Intraperitoneal Mice Mice, SCID Molecular Dynamics Simulation Obesity--drug therapy Oligopeptides--chemistry Peptidomimetics--chemistry Protein Array Analysis RNA, Small Interfering--metabolism Receptors, Adiponectin--agonists Signal Transduction Tumor Burden--drug effects Xenograft Model Antitumor Assays