Safi, Roya

Optimized quantities of GDNF overexpressed by engineered astrocytes are critical for protection of neuroblastoma cells against 6-OHDA toxicity. [electronic resource] - Journal of molecular neuroscience : MN Mar 2012 - 654-65 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1559-1166

10.1007/s12031-011-9654-8 doi


Animals
Apoptosis--drug effects
Astrocytes--pathology
Astrocytoma--genetics
Cell Death--drug effects
Cell Line, Tumor
Cytoprotection--genetics
Feasibility Studies
Genetic Engineering--methods
Genetic Vectors--genetics
Glial Cell Line-Derived Neurotrophic Factor--genetics
HEK293 Cells
Humans
Mice
Mice, Inbred C57BL
Neuroblastoma--genetics
Oxidopamine--toxicity
Parkinson Disease--metabolism
Sympatholytics--toxicity