TY  - GEN
AU  - Onojafe,Ighovie F
AU  - Adams,David R
AU  - Simeonov,Dimitre R
AU  - Zhang,Jun
AU  - Chan,Chi-Chao
AU  - Bernardini,Isa M
AU  - Sergeev,Yuri V
AU  - Dolinska,Monika B
AU  - Alur,Ramakrishna P
AU  - Brilliant,Murray H
AU  - Gahl,William A
AU  - Brooks,Brian P
TI  - Nitisinone improves eye and skin  pigmentation defects in a mouse model  of oculocutaneous albinism
SN  - 1558-8238
PY  - 2011///1121
KW  - Albinism, Oculocutaneous
KW  - drug therapy
KW  - Animals
KW  - Cyclohexanones
KW  - therapeutic use
KW  - Disease Models, Animal
KW  - Enzyme Inhibitors
KW  - Enzyme Stability
KW  - drug effects
KW  - Eye Color
KW  - Female
KW  - Humans
KW  - Melanins
KW  - metabolism
KW  - Melanocytes
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Mutant Strains
KW  - Microscopy, Electron, Transmission
KW  - Models, Molecular
KW  - Monophenol Monooxygenase
KW  - chemistry
KW  - Mutation
KW  - Nitrobenzoates
KW  - Pregnancy
KW  - Skin Pigmentation
KW  - Tyrosine
N1  - Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/JCI59372
ER  -