TY  - GEN
AU  - Jung,Donald
AU  - Lin,Lin
AU  - Jiao,Hailong
AU  - Cai,Xiaohong
AU  - Duan,Jian-Xin
AU  - Matteucci,M
TI  - Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys
SN  - 1432-0843
PY  - 2012///0420
KW  - Administration, Oral
KW  - Animals
KW  - Dogs
KW  - Drug Evaluation, Preclinical
KW  - Female
KW  - Half-Life
KW  - Humans
KW  - Hypoxia
KW  - metabolism
KW  - Infusions, Intravenous
KW  - Injections, Intraperitoneal
KW  - Injections, Intravenous
KW  - Macaca fascicularis
KW  - Male
KW  - Mice
KW  - Mice, Inbred Strains
KW  - Mice, Nude
KW  - Molecular Structure
KW  - Nitroimidazoles
KW  - administration & dosage
KW  - Phosphoramide Mustards
KW  - Predictive Value of Tests
KW  - Prodrugs
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Species Specificity
KW  - Tissue Distribution
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s00280-011-1741-6
ER  -