Jung, Donald <br/><br/>
Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys.  [electronic resource] 

 -  Cancer chemotherapy and pharmacology  Mar 2012 
 - 643-54 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1432-0843 
<br/><br/><label>Standard No.: </label>10.1007/s00280-011-1741-6  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Dogs<br/>Drug Evaluation, Preclinical<br/>Female<br/>Half-Life<br/>Humans<br/>Hypoxia--metabolism<br/>Infusions, Intravenous<br/>Injections, Intraperitoneal<br/>Injections, Intravenous<br/>Macaca fascicularis<br/>Male<br/>Mice<br/>Mice, Inbred Strains<br/>Mice, Nude<br/>Molecular Structure<br/>Nitroimidazoles--administration & dosage<br/>Phosphoramide Mustards--administration & dosage<br/>Predictive Value of Tests<br/>Prodrugs--administration & dosage<br/>Rats<br/>Rats, Sprague-Dawley<br/>Species Specificity<br/>Tissue Distribution