Yu, Teng <br/><br/>
1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation.  [electronic resource] 

 -  Molecular and cellular biochemistry  Feb 2012 
 - 47-54 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1573-4919 
<br/><br/><label>Standard No.: </label>10.1007/s11010-011-1086-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Ceramides--metabolism<br/>Curcumin--pharmacology<br/>Drug Synergism<br/>Enzyme Activation<br/>Humans<br/>JNK Mitogen-Activated Protein Kinases--metabolism<br/>Melanoma<br/>Morpholines--pharmacology<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Proto-Oncogene Proteins c-akt--antagonists & inhibitors