Mitch, Charles H <br/><br/>
Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2011 
 - 8000-12 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm200789r  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Benzamides--chemical synthesis<br/>Brain--metabolism<br/>CHO Cells<br/>Chromatography, Liquid<br/>Cricetinae<br/>Cricetulus<br/>HEK293 Cells<br/>Humans<br/>Pyrrolidines--chemical synthesis<br/>Radioligand Assay<br/>Rats<br/>Receptors, Opioid, kappa--antagonists & inhibitors<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Tandem Mass Spectrometry