Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug. [electronic resource]
- British journal of pharmacology Apr 2012
- 2127-39 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1476-5381
10.1111/j.1476-5381.2011.01702.x doi
Animals Bone Neoplasms--drug therapy Bone Resorption--drug therapy Cell Line Colchicine--analogs & derivatives Enzyme Activation--drug effects Female Humans I-kappa B Kinase--metabolism Inflammation--prevention & control Liliaceae--chemistry Male Mice NF-kappa B--metabolism Osteoclasts--drug effects Phytotherapy RANK Ligand--physiology Signal Transduction--drug effects