TY - GEN AU - Xu,You-Zhi AU - Zheng,Ren-Lin AU - Zhou,Yan AU - Peng,Feng AU - Lin,Hong-Jun AU - Bu,Qian AU - Mao,Yong-Qiu AU - Yu,Luo-Ting AU - Yang,Li AU - Yang,Sheng-Yong AU - Zhao,Ying-Lan TI - Small molecular anticancer agent SKLB703 induces apoptosis in human hepatocellular carcinoma cells via the mitochondrial apoptotic pathway invitro and inhibits tumor growth invivo SN - 1872-7980 PY - 2012///0109 KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Carcinoma, Hepatocellular KW - drug therapy KW - Caspases KW - metabolism KW - Dose-Response Relationship, Drug KW - Enzyme Activation KW - Female KW - Hep G2 Cells KW - Humans KW - K562 Cells KW - Liver Neoplasms, Experimental KW - Male KW - Membrane Potential, Mitochondrial KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Mitochondria KW - Mitogen-Activated Protein Kinases KW - Phosphorylation KW - Pyridines KW - Rats KW - Rats, Sprague-Dawley KW - Thiophenes KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.canlet.2011.08.025 ER -