TY - GEN AU - Kline,Christina Leah AU - Sheikh,Hassan S AU - Scicchitano,Angelique AU - Gingrich,Rebecca AU - Beachler,Cheryl AU - Finnberg,Niklas K AU - Liao,Jason AU - Sivik,Jeffrey AU - El-Deiry,Wafik S TI - Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients SN - 1555-8576 PY - 2012///0328 KW - Adult KW - Aged KW - Antimetabolites, Antineoplastic KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Area Under Curve KW - Camptothecin KW - analogs & derivatives KW - Colorectal Neoplasms KW - drug therapy KW - Dose-Response Relationship, Drug KW - Female KW - Fluorouracil KW - Humans KW - Infusions, Intravenous KW - Leucovorin KW - Male KW - Middle Aged KW - Organoplatinum Compounds KW - Proto-Oncogene Proteins KW - genetics KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins p21(ras) KW - Thymidylate Synthase KW - ras Proteins N1 - Publication Type: Clinical Trial; Journal Article UR - https://doi.org/10.4161/cbt.12.7.18059 ER -