Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients. [electronic resource]
- Cancer biology & therapy Oct 2011
- 557-68 p. digital
Publication Type: Clinical Trial; Journal Article
1555-8576
10.4161/cbt.12.7.18059 doi
Adult Aged Antimetabolites, Antineoplastic--administration & dosage Antineoplastic Combined Chemotherapy Protocols--therapeutic use Area Under Curve Camptothecin--analogs & derivatives Colorectal Neoplasms--drug therapy Dose-Response Relationship, Drug Female Fluorouracil--administration & dosage Humans Infusions, Intravenous Leucovorin--therapeutic use Male Middle Aged Organoplatinum Compounds--therapeutic use Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins B-raf--genetics Proto-Oncogene Proteins p21(ras) Thymidylate Synthase--genetics ras Proteins--genetics